The South African government has indicated that pregnant women may be vaccinated when the benefit of vaccinating (e.g. health workers at high risk of exposure or pregnant women with co-morbidities) outweighs the potential vaccine risks. SARS-CoV-2 vaccine trials excluded pregnant woman from participation so there are fewer data on vaccine safety during pregnancy. However, as the vaccine has been rolled out, women who did not know they were pregnant were vaccinated. Their experiences are being monitored globally, even in South Africa. To date, no negative effects have been reported. It is helpful to know that all COVID-19 vaccines that have been rolled out were tested on pregnant animals and no adverse effects were reported. The WHO does not recommend pregnancy testing before COVID-19 vaccination.